Trim the fat and silver skin off the pork tenderloin if necessary.
In shallow bowl, combine olive oil, mustard, grainy mustard, lemon juice, garlic, salt, pepper, and oregano and mix well. Add tenderloin and turn to coat.
Cover and marinated in refrigerator at least 8 hours.
When ready to cook, preheat oven to 450°F.
Heat a tablespoon of oil in a cast iron skillet over high heat on the stove top. When the oil is hot, place the pork tenderloin on the skillet. (Discard the marinade.) Allow it to sear on each side for a minute, turning to sear all the way around.
Place the skillet in the oven and reduce the heat to 350°F. Roast the pork tenderloin for 27-35 minutes or until a meat thermometer registers 155°F. (The time it takes will depend on the thickness of the tenderloin, so keep an eye on it.)
Remove the skillet from the oven. Tent with a piece of foil and let stand 10 minutes before slicing to serve.